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Test ID PBORB Lyme Disease, Molecular Detection, PCR, Blood

Useful For

Supporting the diagnosis of Lyme disease in conjunction with serologic testing

Method Name

Real-Time Polymerase Chain Reaction (PCR)/DNA Probe Hybridization

Reporting Name

Lyme Disease PCR, B

Specimen Type

Whole Blood EDTA

Ordering Guidance

This assay does not detect Borrelia miyamotoi. If infection with this organism is suspected, order BMIYB / Borrelia miyamotoi Detection PCR, Blood or BMIYC / Borrelia miyamotoi Detection PCR, Spinal Fluid.

Specimen Required

Container/Tube: Lavender top (EDTA)

Specimen Volume: 1 mL

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values


Day(s) Performed

June through November: Monday through Saturday

December through May: Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


87798 x 2

87999 (if appropriate for government payers)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PBORB Lyme Disease PCR, B 90892-1


Result ID Test Result Name Result LOINC Value
56080 B. burgdorferi PCR, B 94247-4
38290 B. mayonii PCR, B 94248-2
38291 B. garinii/B. afzelii PCR, B 94249-0
38340 Lyme Disease PCR Comment 59464-8

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Report Available

1 to 4 days

NY State Approved


Testing Algorithm

See Acute Tick-Borne Disease Testing Algorithm in Special Instructions


If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.