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Test ID PLAIF Phospholipase A2 Receptor (PLA2R), Renal Biopsy

Ordering Guidance

This test will report as negative or positive for autoantibodies to phospholipase A2 receptor (PLA2R).


If additional interpretation/analysis is needed, request PATHC / Pathology Consultation along with this test and send the corresponding renal pathology light microscopy and immunofluorescence (IF) slides (or IF images on a CD), electron microscopy images (prints or CD), and the pathology report.

Shipping Instructions

1. Advise shipping specimens in Styrofoam transportation coolers to avoid extreme hot or cold temperatures to ensure specimens are received at required specimen stability temperature.

2. Attach the green pathology address label included in the kit to the outside of the transport container.

Necessary Information

A pathology/diagnostic report is required.

Specimen Required

Preferred: Frozen tissue

Supplies: Renal Biopsy Kit (T231)

Specimen Type: Kidney tissue

Container/Tube: Renal Biopsy Kit, Zeus/Michel's, Frozen

Specimen Volume: Entire specimen

Collection Instructions: Collect specimens according to the instructions in Renal Biopsy Procedure for Handling Tissue for Light Microscopy (LM), Immunofluorescent Histology (IF), and Electron Microscopy (EM) in Special Instructions.

Additional Information: If standard immunoglobulin and complement immunofluorescence has already been performed, submit the residual frozen tissue (must contain glomeruli) on dry ice.


Acceptable: Frozen tissue

Slides: 2 frozen tissue unstained positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick, submitted on dry ice.


1. Renal Biopsy Patient Information in Special Instructions

2. If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Method Name


Reporting Name

PLA2R Immunofluorescence

Specimen Type


Specimen Stability Information

Specimen Type Temperature Time Special Container
Special Frozen (preferred)

Day(s) Performed

Monday through Friday

Report Available

1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

88346-primary IF

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PLAIF PLA2R Immunofluorescence In Process


Result ID Test Result Name Result LOINC Value
71225 Interpretation 59465-5
71226 Participated in the Interpretation No LOINC Needed
71227 Report electronically signed by 19139-5
71228 Addendum 35265-8
71229 Gross Description 22634-0
71230 Material Received 81178-6
71617 Disclaimer 62364-5
71847 Case Number 80398-1

NY State Approved