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HelpTest ID PM3CX Lymph3Cx Assay, Primary Mediastinal Large B-cell Lymphoma and Diffuse Large B-cell Lymphoma, mRNA Gene Expression, NanoString, Tissue
Ordering Guidance
This test does not include a pathology consultation. If a pathology consultation is requested, PATHC / Pathology Consultation will be ordered and performed at an additional charge.
Necessary Information
Pathology report (final or preliminary) must accompany specimen in order for testing to be performed. At minimum, it should contain the following information:
1. Patient name
2. Block number-must be on all blocks, slides, and paperwork (can be handwritten on the paperwork)
3. Tissue collection date
4. Source of the tissue
Specimen Required
Submit only 1 of the following specimens:
Preferred:
Specimen Type: Tissue slides
Slides: 1 stained and 7 unstained
Collection Instructions: Submit 1 slide stained with hematoxylin and eosin and 7 consecutive, unstained, 5-micron thick sections placed on positively charged slides.
Additional Information: Paraffin embedded specimens can be from any anatomic location (skin, soft tissue, lymph node, etc).
Acceptable:
Specimen Type: Tissue block
Collection Instructions: Submit a formalin-fixed, paraffin-embedded tumor tissue block.
Useful For
Only indicated for formalin-fixed paraffin-embedded specimens from patients diagnosed with large B-cell lymphoma
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| AZSLR | Slide Review | No, (Bill Only) | Yes |
Testing Algorithm
When this test is ordered, slide review will always be performed at an additional charge.
Method Name
Gene Expression by Digital Counting of Fluorescent Bar-Coded Probes
Reporting Name
Lymph3Cx, Lg Bcell Lymphoma,mRNA,TsSpecimen Type
Tissue, ParaffinSpecimen Minimum Volume
Minimum 60% tumor with or without macrodissection.
Minimum required unstained tissue section input: 0.12 mm(3)
Slides: If the tumor surface area is less than or equal to 4 mm(2), submit a minimum of 3 slides; if the tumor surface area is 5 to 11 mm(2), submit a minimum of 2 slides; if the tumor surface area is greater than 11 mm(2), submit a minimum of 1 slide.
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Tissue, Paraffin | Ambient (preferred) | ||
| Refrigerated | |||
Reference Values
Not applicable
Day(s) Performed
Monday through Friday
Report Available
7 to 12 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
0120U
88381
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PM3CX | Lymph3Cx, Lg Bcell Lymphoma,mRNA,Ts | 93785-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 606164 | Lymph3Cx, Large B-cell Lymphoma, mRNA, Tissue | 93779-7 |
| 606165 | PMBCL Probability | 93780-5 |
| 606185 | PMBCL Call | 93782-1 |
| 606166 | DLBCL Probability | 93781-3 |
| 606186 | DLBCL COO | 93783-9 |