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Test ID PNTOR Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum


Ordering Guidance


This test is the preferred test for patients being evaluated for possible immunodeficiency or for assessment of pneumococcal vaccination response (initial evaluation).

 

The preferred test for patients previously tested for Streptococcus pneumoniae antibodies (as part of follow up testing or part of pre/post vaccine assessment) is PNTO / Streptococcus pneumoniae IgG Antibodies, Total, Serum.

 

The preferred test for patients previously tested for S pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment) is PN23 / Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum.



Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL


Useful For

Assessing the IgG antibody response to active immunization with nonconjugated 23-valent vaccines

 

Assessing the IgG antibody response to active immunization with conjugated 13-valent and 7-valent vaccines

 

Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of an evaluation for humoral or combined immunodeficiencies

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
PN23 S. pneumoniae IgG Ab,23 serotypes,S Yes No

Testing Algorithm

If the result is 41.0 mcg/mL or greater and less than 181.0 mcg/mL, then Streptococcus pneumoniae IgG antibodies for 23 serotypes will be performed at an additional charge.

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA) 

Reporting Name

S. pneumoniae IgG Ab, with reflex,S

Specimen Type

Serum

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reference Values

≥9.7 mcg/mL

Day(s) Performed

Tuesday, Thursday

Report Available

4 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86317

86317 x 23 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PNTOR S. pneumoniae IgG Ab, with reflex,S 43236-9

 

Result ID Test Result Name Result LOINC Value
PNTOR S. pneumoniae IgG Ab, with reflex,S 43236-9

NY State Approved

Yes