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Test ID RMPSU Monoclonal Protein Study, Random, Urine

Useful For

Diagnosing monoclonal gammopathies

Method Name

PTCON: Turbidimetry

RPEU: Agarose Gel Electrophoresis

RIFXU: Immunofixation

Reporting Name

Monoclonal Protein Study, Random, U

Specimen Type

Urine


Advisory Information


The use of a random urine specimen is sufficient for identifying the presence or absence of a monoclonal immunoglobulin, but a 24-hour specimen is preferred for quantitating and monitoring the abnormality. See MPSU / Monoclonal Protein Study, 24 Hour, Urine.



Shipping Instructions


Refrigerate specimen during collection and send refrigerated.



Necessary Information


Random urine, no volume is required.



Specimen Required


Supplies: Aliquot Tube, 5 mL (T465)

Container/Tube: Plastic, 60-mL urine bottle and plastic, 5-mL tube (T465)

Specimen Volume: 50 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Aliquot specimen between containers.

3. Label specimens appropriately (60-mL urine bottle for protein electrophoresis and immunofixation and 5-mL tube for protein, total).


Specimen Minimum Volume

25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  5 days
  Ambient  72 hours

Reference Values

PROTEIN, TOTAL

No reference values apply to random urine.

 

ELECTROPHORESIS, PROTEIN

The following fractions, if present, will be reported as a percent of the total protein:

Albumin

Alpha-1-globulin

Alpha-2-globulin

Beta-globulin

Gamma-globulin

Day(s) and Time(s) Performed

Protein, Total: Monday through Sunday; Continuously

Electrophoresis, Protein: Monday through Saturday; 12 p.m.

Immunofixation: Monday through Saturday; 8 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84156

84166

86335

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RMPSU Monoclonal Protein Study, Random, U In Process

 

Result ID Test Result Name Result LOINC Value
33039 Albumin 13992-3
33040 Alpha 1-Globulin 13990-7
33041 Alpha 2-Globulin 13993-1
33042 Beta-Globulin 13994-9
33043 Gamma-Globulin 13995-6
33044 A/G Ratio 44293-9
33045 M spike 42483-8
33046 M spike 42483-8
33047 Impression 49299-1
PTCON Protein, Total, Random, U 2888-6
32526 Immunofixation, Random, U 74666-9

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

NY State Approved

Yes

Testing Algorithm

The following algorithms are available in Special Instructions:

-Laboratory Approach to the Diagnosis of Amyloidosis

-Laboratory Screening Tests for Suspected Multiple Myeloma

Profile Information

Test ID Reporting Name Available Separately Always Performed
RPEU Protein Electrophoresis, Random, U No Yes
RIFXU Immunofixation, Random, U No Yes
PTCON Protein, Total, Random, U No Yes

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection. 

Ambient

Yes

Refrigerate

Preferred

Frozen

Yes

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

Yes

Toluene

Yes

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.