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Test ID RPRT Rapid Plasma Reagin (RPR), Response to Therapy, Serum

Useful For

Determining the current disease status and evaluating response to therapy for syphilis


This assay provides a rapid plasma reagin (RPR) titer and can be used to monitor response to therapy in patients treated for syphilis infection.

Method Name


Reporting Name

RPR, Response to Therapy, S

Specimen Type


Advisory Information

This test is not intended for medical-legal use.


This test is for monitoring response to therapy in patients treated for syphilis infection. This test should not be used as a primary diagnostic approach for syphilis.


To screen for undiagnosed syphilis infection, order SYPGR / Syphilis IgG Antibody with Reflex, Serum.

Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values


Day(s) and Time(s) Performed

Monday through Saturday; 8 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
RPRT RPR, Response to Therapy, S 31147-2


Result ID Test Result Name Result LOINC Value
31696 RPR, Response to Therapy, S 31147-2

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
RRPRQ RPR Titer, S No No

Testing Algorithm

If this test is positive, RPR titer will be performed at an additional charge.