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Test ID SNTX N-terminal Telopeptide, Serum


Specimen Required


Patient Preparation: Fasting is preferred due to diurnal variation of markers and food effects

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: A morning collection from fasting patients is preferred. If not possible, collect the baseline and subsequent specimens under the same circumstances (eg, at same time of day).


Useful For

Monitoring effectiveness of antiresorptive therapy in patients treated for osteoporosis or other metabolic bone disorders

 

As an adjunct in the diagnosis of medical conditions associated with increased bone turnover

 

This test is not useful for screening or diagnosing osteoporosis.

Highlights

Measurement of serum N-terminal telopeptide (NTx) is helpful for monitoring effectiveness of antiresorptive therapies in patients treated for osteoporosis or other metabolic bone disorders.

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

NTX-Telopeptide, S

Specimen Type

Serum

Specimen Minimum Volume

0.1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 28 days
  Refrigerated  24 hours

Reference Values

All units are reported in nmol bone collagen equivalents (BCE)

Adult (≥18 years of age)

 

Males:

5.4-24.2 nmol BCE

 

Females:

Premenopausal: 6.2-19.0 nmol BCE

The target value for postmenopausal adult females undergoing treatment for osteoporosis is the same as the premenopausal reference interval.

Day(s) Performed

Tuesday, Thursday

Report Available

1 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82523

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SNTX NTX-Telopeptide, S 21215-9

 

Result ID Test Result Name Result LOINC Value
65558 NTX-Telopeptide, S 21215-9

NY State Approved

Yes