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Test ID SPNC Streptococcus pneumoniae Antigen, Spinal Fluid

Useful For

Rapid diagnosis of pneumococcal meningitis

Method Name

Immunochromatographic Membrane Assay

Reporting Name

Streptococcus pneumoniae Ag, CSF

Specimen Type


Additional Testing Requirements

According to the College of American Pathologists (CAP, IMM.41830), cerebrospinal fluid (CSF) samples collected to make an initial diagnosis and submitted for detection of Streptococcus pneumoniae antigen testing should also be submitted for routine bacterial culture. Mayo Clinic Laboratories recommends that CSF bacterial cultures be performed at the originating site.

Specimen Required

Container/Tube: Sterile vial

Specimen Volume: 1 mL

Collection Instructions: Submit specimen collected in vial 2, if possible. If not possible, note which vial from which the aliquot was obtained.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values


Reference values apply to all ages.

Day(s) Performed

Monday through Sunday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
SPNC Streptococcus pneumoniae Ag, CSF 20489-1


Result ID Test Result Name Result LOINC Value
31667 Streptococcus pneumoniae Ag, CSF 20489-1

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

Same day/1 day

NY State Approved



If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.