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Test ID SPSA Prostate-Specific Antigen (PSA) Screen, Serum

Useful For

Monitoring patients with a history of prostate cancer as an early indicator of recurrence and response to treatment


Prostate cancer screening

Method Name

Electrochemiluminescent Immunoassay

Reporting Name

Prostate-Specific Ag Screen, S

Specimen Type


Ordering Guidance

Free prostate-specific antigen (PSA) can be added to previously-submitted PSA screen specimen within 12 hours of performing the total PSA. Specimen must have been shipped frozen.


If both free and total PSA are requested, order PSAFT / Prostate-Specific Antigen (PSA), Total and Free, Serum.

Necessary Information

Include patient's age.

Specimen Required

Patient Preparation: For 12 hours before specimen collection, do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Red-top tube must be centrifuged and aliquoted within 2 hours of collection.

2. Serum gel tube must be centrifuged within 2 hours of collection.

Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 180 days
  Refrigerated  5 days

Reference Values


Age (years)

PSA upper limit (ng/mL)














Females: Not applicable

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


G0103 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SPSA Prostate-Specific Ag Screen, S 83112-3


Result ID Test Result Name Result LOINC Value
SPSA Prostate-Specific Ag Screen, S 83112-3

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

1 to 3 days

NY State Approved