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Test ID SYPHN Syphilis Total Antibody, Serum

Specimen Required

Collection Container/Tube: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum


If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.

Useful For

An aid in the diagnosis of recent or past Treponema pallidum infection


Routine prenatal screening


This test is not useful for diagnosis of congenital syphilis.


This test is not offered as a screening or confirmatory test for blood donor specimens.


This testing should be used to assess for recent or past infection with Treponema pallidum or for routine prenatal screening.


Testing for syphilis is performed using the reverse screening algorithm at Mayo Clinic and Mayo Clinic Laboratories.

Method Name

Multiplex Flow Immunoassay

Reporting Name

Syphilis Total Ab, S

Specimen Type


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values


Day(s) and Time(s) Performed

Monday through Saturday; 9 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
SYPHN Syphilis Total Ab, S 47236-5


Result ID Test Result Name Result LOINC Value
SYPHN Syphilis Total Ab, S 47236-5

NY State Approved