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HelpTest ID TCGRV T-Cell Receptor Gene Rearrangement, PCR, Varies
Useful For
Determining whether a T-cell population is polyclonal or monoclonal using body fluid or tissue specimens
Special Instructions
Method Name
Polymerase Chain Reaction (PCR)
Reporting Name
T Cell Receptor Gene Rearrange, VSpecimen Type
VariesShipping Instructions
Body fluid or spinal fluid specimens must arrive within 4 days (96 hours) of collection.
Specimen Required
Submit only 1 of the following specimens:
Specimen Type: Body fluid
Container/Tube: Sterile container
Specimen Volume: At least 5 mL
Collection Instructions:
1. If the volume is large, pellet cells prior to sending.
2. Send less volume at ambient temperature or as a frozen cell pellet.
Specimen Stability Information:
Body fluid: Ambient/Refrigerated/Frozen
Cell pellet: Frozen
Specimen Type: Paraffin-embedded bone marrow aspirate clot
Container/Tube: Paraffin block
Specimen Stability Information: Ambient
Specimen Type: Frozen tissue
Container/Tube: Plastic container
Specimen Volume: 100 mg
Collection Instructions: Freeze tissue within 1 hour of collection.
Specimen Stability Information: Frozen
Specimen Type: Paraffin-embedded tissue
Container/Tube: Paraffin block
Specimen Stability Information: Ambient
Specimen Type: Tissue slides
Container/Tube: Unstained tissue slides
Specimen Volume: 10 slides
Specimen Stability: Ambient
Specimen Type: Spinal fluid
Container/Tube: Sterile vial
Specimen Volume: 5-10 mL
Specimen Stability Information: Ambient/Refrigerated
Specimen Type: Extracted DNA from blood or bone marrow
Container/Tube: 1.5- to 2-mL tube with indication of volume and concentration of DNA
Specimen Volume: Entire specimen
Collection Instructions: Label specimen as extracted DNA from blood or bone marrow
Specimen Stability Information: Refrigerated/Ambient
Specimen Minimum Volume
Body fluid or Spinal fluid: 1 mL
Tissue: 50 mg
Extracted DNA from Blood or Bone Marrow:
50 microliters at 20 ng/mcL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Varies | Varies | ||
Reference Values
An interpretive report will be provided.
Positive, negative, or indeterminate for a clonal T-cell population
Day(s) and Time(s) Performed
Monday through Friday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
81340-TCB (T cell antigen receptor, beta) (eg, leukemia and lymphoma), gene rearrangement analysis to detect abnormal clonal population(s); using amplification methodology (eg, PCR)
81342-TCG@ (T cell receptor, gamma) (eg, leukemia and lymphoma), gene rearrangement analysis, evaluation to detect abnormal clonal population(s)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TCGRV | T Cell Receptor Gene Rearrange, V | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 19936 | Final Diagnosis: | 22637-3 |
| MP016 | Specimen: | 31208-2 |
| 608953 | Signing Pathologist | 19139-5 |
Test Classification
This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.NY State Approved
YesForms
1. Hematopathology Patient Information (T676) in Special Instructions
2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.