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Test ID TXMGP Toxoplasma gondii Antibody, IgM and IgG, Serum

Useful For

Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii


IgG is not useful for diagnosing infection in infants younger than 6 months of age. IgG antibodies in this age group usually are the result of passive transfer from the mother.


Detection of IgM-class antibodies to Toxoplasma gondii may be useful as a screen for recent infection with Toxoplasma gondii.


Per the FDA, IgM-positive results by a screening assay should be confirmed, for example by a Toxoplasma reference laboratory.


A single negative result by this assay does not rule-out toxoplasmosis as the specimen may have been collected too early following infection, prior to development of detectable antibodies.


A single IgG-positive result is indicative of exposure to Toxoplasma gondii at some time in the past.

Profile Information

Test ID Reporting Name Available Separately Always Performed
TXM Toxoplasma Ab, IgM, S Yes Yes
TOXGP Toxoplasma Ab, IgG, S Yes Yes

Method Name

Multiplex Flow Immunoassay (MFI)

Reporting Name

Toxoplasma Ab, IgM and IgG, S

Specimen Type


Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Aliquot tube

Specimen Volume: 1.5 mL

Specimen Minimum Volume

1.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values

Toxoplasma IgM



Toxoplasma IgG



Toxoplasma IgG Value

≤9 IU/mL (Negative)

10-11 IU/mL (Equivocal)

≥12 IU/mL (Positive)

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86778-Toxoplasma IgM

86777-Toxoplasma IgG

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TXMGP Toxoplasma Ab, IgM and IgG, S 88746-3


Result ID Test Result Name Result LOINC Value
TOXG Toxoplasma Ab, IgG, S 40677-7
TXM Toxoplasma Ab, IgM, S 40678-5
DEXG6 Toxoplasma IgG Value 8039-0

NY State Approved



If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Testing Algorithm

See Meningitis/Encephalitis Panel Algorithm in Special Instructions.