Test ID UE3 Estriol, Unconjugated, Serum
Useful For
A part of second trimester or cross-trimester biochemical screening for Down syndrome and trisomy 18 syndrome
A marker of fetal demise
An adjunct biomarker in the prenatal diagnosis of disorders of fetal steroid metabolism, including Smith-Lemli-Opitz syndrome (SLO)(3-4), and X-linked ichthyosis (placental sulfatase deficiency disorders)
Evaluating primary or secondary fetal adrenal insufficiency after excluding other rare single gene defects, including aromatase deficiency, 17 alpha-hydroxylase deficiency and/or various forms of congenital adrenal hyperplasia
Method Name
Immunoenzymatic Assay
Reporting Name
Estriol, Unconjugated, SSpecimen Type
SerumSpecimen Required
Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Specimen Volume: 0.6 mL
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 14 days | |
Frozen | 90 days |
Reference Values
Males: <0.07 ng/mL
Females: <0.08 ng/mL
For SI unit Reference Values, see https://www.mayocliniclabs.com/order-tests/si-unit-conversion.html
Day(s) Performed
Monday through Friday
Performing Laboratory

CPT Code Information
82677
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
UE3 | Estriol, Unconjugated, S | 2250-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
UE3 | Estriol, Unconjugated, S | 2250-9 |