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Test ID VLTB Volatile Screen, Blood

Useful For

Detection and quantitation of acetone, methanol, isopropanol, and ethanol in whole blood


Quantification of the concentration of ethanol in blood that correlates with the degree of intoxication


Evaluation of toxicity to the measured volatile substances


This test is not intended for use in employment-related testing.

Method Name

Headspace Gas Chromatography-Flame Ionization Detector (HSGC-FID)

Reporting Name

Volatile Scrn, B

Specimen Type

Whole blood

Ordering Guidance

This test is not performed using chain of custody. For chain of custody testing order VLTBX / Volatile Screen, Chain of Custody, Blood.

Additional Testing Requirements

Ethylene glycol requires a separate request. See ETGL / Ethylene Glycol, Serum.

Specimen Required


Preferred: Grey top (potassium oxalate/sodium fluoride)

Acceptable: Any anticoagulant

Specimen Volume: 1 mL

Collection Instructions: Do not use alcohol to clean arm. Use alternatives such as Betadine to cleanse arm before collecting any specimen for volatile testing.

Specimen Minimum Volume

0.5 mL or amount to fill 1 tube

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  24 hours

Reference Values


Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL



Not detected (Positive results are quantitated.)

Toxic concentration: ≥400 mg/dL



Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL



Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL

Day(s) Performed

Monday through Sunday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VLTB Volatile Scrn, B 41266-8


Result ID Test Result Name Result LOINC Value
89190 Volatile Scrn, B 41266-8
30921 Methanol, B 9334-4
30922 Ethanol, B 5640-8
30923 Acetone, B 9425-0
30924 Isopropanol, B 5667-1
34377 Chain of Custody 77202-0

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Report Available

Same day/1 day

NY State Approved


Testing Algorithm

This test includes analysis of methanol, ethanol, isopropanol, and acetone.